Those infected with lycanthropy may become Werewolves. During the day, these people appear to be human, albeit with some features that suggest at their condition such as protruding canines or significant body hair. At night under the full moon though, these being are transformed into a hunched wolf-like therianthropic hybrid creature that looks like a human, but fur covers its body. Its face is wolf-like, and it displays gigantic fangs and horrific claws. It grows taller and heavier with long, powerful arms, thick skin and bones, heavy fur, and a large wolf tail for balance and body language. Its awful mouth can barely speak human words, though it can bay and howl with deafening eloquence. Unlike the Wererat, a Werewolf's surging rage reduces it to little more than a thoughtless killing machine, and the lycanthrope wakes at daylight naked and covered in blood with no knowledge of what transpired during the night of the full moon.

I've made werewolfs canonically like hybrid killing machines like the rats. However, I could see a case where a lycanthrope manages to gain control of their disease so they can transform into a full rat/werewolf. Those might be special cases, though and perhaps only allowed for special NPC villians.